ID   LM-MEL-42
AC   CVCL_UC48
SY   LM-Mel-42; Ludwig Melbourne-MELanoma-42
DR   ArrayExpress; E-MTAB-1496
DR   ATCC; CRL-3335
DR   cancercelllines; CVCL_UC48
DR   GEO; GSM2371773
DR   Wikidata; Q95982535
RX   PubMed=19221743;
RX   PubMed=23527996;
RX   PubMed=27852308;
CC   Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
CC   Doubling time: ~38 hours (ATCC=CRL-3335).
CC   HLA typing: A*11:01,02:01; B*55,27; C*03 (PubMed=23527996).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Unspecified (PubMed=23527996).
CC   Omics: miRNA expression profiling.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: STR profile from personal communication of Cardwell T., Olivia Newton-John Cancer Research Institute.
CC   Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106.
ST   Source(s): ATCC=CRL-3335; Direct_author_submission
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 11
ST   D16S539: 12
ST   D21S11: 29
ST   D5S818: 10,12
ST   D7S820: 10,11
ST   TH01: 6,9.3
ST   TPOX: 8
ST   vWA: 17,18
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   67Y
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 02-05-24; Version: 8
//
RX   PubMed=19221743; DOI=10.1007/s00262-009-0672-0;
RA   Gedye C., Quirk J., Browning J., Svobodova S., John T., Sluka P.,
RA   Dunbar P.R., Corbeil D., Cebon J.S., Davis I.D.;
RT   "Cancer/testis antigens can be immunological targets in clonogenic
RT   CD133+ melanoma cells.";
RL   Cancer Immunol. Immunother. 58:1635-1646(2009).
//
RX   PubMed=23527996; DOI=10.1111/pcmr.12097;
RA   Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J.,
RA   Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.;
RT   "The Ludwig Institute for Cancer Research Melbourne melanoma cell line
RT   panel.";
RL   Pigment Cell Melanoma Res. 26:597-600(2013).
//
RX   PubMed=27852308; DOI=10.1186/s12943-016-0554-y;
RA   Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S.,
RA   Behren A., Crampin E.J.;
RT   "Systems analysis identifies miR-29b regulation of invasiveness in
RT   melanoma.";
RL   Mol. Cancer 15:72.1-72.20(2016).
//