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Cellosaurus LM-MEL-26 (CVCL_UC34)

[Text version]
Cell line name LM-MEL-26
Synonyms LM-Mel-26; Ludwig Melbourne-MELanoma-26
Accession CVCL_UC34
Resource Identification Initiative To cite this cell line use: LM-MEL-26 (RRID:CVCL_UC34)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: MET mutation and STR profile from personal communication of Cardwell T., Olivia Newton-John Cancer Research Institute.
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
  • Mutation; HGNC; 7029; MET; Simple; p.Thr992Ile (c.2975C>T) (p.Thr1010Ile, c.3029C>T); ClinVar=VCV000041624; Zygosity=Heterozygous (Direct_author_submission).
HLA typing Source: PubMed=23527996
Class I
HLA-AA*02:01,24:02
HLA-BB*07:02,27:05
HLA-CC*01:02,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11,13
D5S81811,12
D7S82010
D13S3178,13
D16S53910,11
D21S1129,30
TH017
TPOX10
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=18413770; DOI=10.1158/0008-5472.CAN-07-5664
Ebert L.M., Tan B.S., Browning J., Svobodova S., Russell S.E., Kirkpatrick N.C., Gedye C., Moss D.J., Ng S.P., MacGregor D.P., Davis I.D., Cebon J.S., Chen W.-S.
The regulatory T cell-associated transcription factor FoxP3 is expressed by tumor cells.
Cancer Res. 68:3001-3009(2008)

PubMed=18957296; DOI=10.1016/j.jim.2008.09.023
Dimopoulos N., Jackson H.M., Ebert L., Guillaume P., Luescher I.F., Ritter G., Chen W.-S.
Combining MHC tetramer and intracellular cytokine staining for CD8(+) T cells to reveal antigenic epitopes naturally presented on tumor cells.
J. Immunol. Methods 340:90-94(2009)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UC34
Encyclopedic resources Wikidata; Q95982512
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371759
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number9