ID   LM-MEL-26
AC   CVCL_UC34
SY   LM-Mel-26; Ludwig Melbourne-MELanoma-26
DR   ArrayExpress; E-MTAB-1496
DR   cancercelllines; CVCL_UC34
DR   GEO; GSM2371759
DR   Wikidata; Q95982512
RX   PubMed=18413770;
RX   PubMed=18957296;
RX   PubMed=23527996;
RX   PubMed=27852308;
CC   Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
CC   HLA typing: A*02:01,24:02; B*07:02,27:05; C*01:02,07:02 (PubMed=23527996).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23527996).
CC   Sequence variation: Mutation; HGNC; HGNC:7029; MET; Simple; p.Thr992Ile (c.2975C>T) (p.Thr1010Ile, c.3029C>T); ClinVar=VCV000041624; Zygosity=Heterozygous (Direct_author_submission).
CC   Omics: miRNA expression profiling.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: MET mutation and STR profile from personal communication of Cardwell, Tracy.
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X,Y
ST   CSF1PO: 11,13
ST   D13S317: 8,13
ST   D16S539: 10,11
ST   D21S11: 29,30
ST   D5S818: 11,12
ST   D7S820: 10
ST   TH01: 7
ST   TPOX: 10
ST   vWA: 17,18
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 19-12-24; Version: 11
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RX   PubMed=18413770; DOI=10.1158/0008-5472.CAN-07-5664;
RA   Ebert L.M., Tan B.S., Browning J., Svobodova S., Russell S.E.,
RA   Kirkpatrick N.C., Gedye C., Moss D.J., Ng S.P., MacGregor D.P.,
RA   Davis I.D., Cebon J.S., Chen W.-S.;
RT   "The regulatory T cell-associated transcription factor FoxP3 is
RT   expressed by tumor cells.";
RL   Cancer Res. 68:3001-3009(2008).
//
RX   PubMed=18957296; DOI=10.1016/j.jim.2008.09.023;
RA   Dimopoulos N., Jackson H.M., Ebert L.M., Guillaume P., Luescher I.F.,
RA   Ritter G., Chen W.-S.;
RT   "Combining MHC tetramer and intracellular cytokine staining for CD8(+)
RT   T cells to reveal antigenic epitopes naturally presented on tumor
RT   cells.";
RL   J. Immunol. Methods 340:90-94(2009).
//
RX   PubMed=23527996; DOI=10.1111/pcmr.12097;
RA   Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J.,
RA   Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.;
RT   "The Ludwig Institute for Cancer Research Melbourne melanoma cell line
RT   panel.";
RL   Pigment Cell Melanoma Res. 26:597-600(2013).
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RX   PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703;
RA   Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S.,
RA   Behren A., Crampin E.J.;
RT   "Systems analysis identifies miR-29b regulation of invasiveness in
RT   melanoma.";
RL   Mol. Cancer 15:72.1-72.20(2016).
//