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Cellosaurus B76.1/Huh7 (CVCL_U443)

[Text version]
Cell line name B76.1/Huh7
Synonyms B76.1/Huh-7; B76.1
Accession CVCL_U443
Resource Identification Initiative To cite this cell line use: B76.1/Huh7 (RRID:CVCL_U443)
Comments Population: Japanese.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_U442 (B76/Huh7)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=12097587; DOI=10.1128/JVI.76.15.7736-7746.2002; PMCID=PMC136363
De Tomassi A., Pizzuti M., Graziani R., Sbardellati A., Altamura S., Paonessa G., Traboni C.
Cell clones selected from the Huh7 human hepatoma cell line support efficient replication of a subgenomic GB virus B replicon.
J. Virol. 76:7736-7746(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U443
Encyclopedic resources Wikidata; Q54752833
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number15