ID   B76.1/Huh7
AC   CVCL_U443
SY   B76.1/Huh-7; B76.1
DR   cancercelllines; CVCL_U443
DR   Wikidata; Q54752833
RX   PubMed=12097587;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_U442 ! B76/Huh7
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 15
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RX   PubMed=12097587; DOI=10.1128/JVI.76.15.7736-7746.2002; PMCID=PMC136363;
RA   De Tomassi A., Pizzuti M., Graziani R., Sbardellati A., Altamura S.,
RA   Paonessa G., Traboni C.;
RT   "Cell clones selected from the Huh7 human hepatoma cell line support
RT   efficient replication of a subgenomic GB virus B replicon.";
RL   J. Virol. 76:7736-7746(2002).
//