• Mutation; HGNC; HGNC:12791; WRN; Simple; p.Arg369Ter (c.1105C>T) (c.1336C>T); ClinVar=VCV000005449; Zygosity=Homozygous (PubMed=9230208; Coriell=AG11395).
  

PubMed=1671011; DOI=10.1016/0014-4827(91)90054-X
Saito H., Moses R.E.
Immortalization of Werner syndrome and progeria fibroblasts.
Exp. Cell Res. 192:373-379(1991)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=9230208
Bennett S.E., Umar A., Oshima J., Monnat R.J. Jr., Kunkel T.A.
Mismatch repair in extracts of Werner syndrome cell lines.
Cancer Res. 57:2956-2960(1997)

PubMed=10606667; DOI=10.1093/nar/28.2.648; PMCID=PMC102521
Moser M.J., Kamath-Loeb A.S., Jacob J.E., Bennett S.E., Oshima J., Monnat R.J. Jr.
WRN helicase expression in Werner syndrome cell lines.
Nucleic Acids Res. 28:648-654(2000)

CLPUB00712
Henson J.D.
The role of alternative lengthening of telomeres in human cancer.
Thesis PhD (2006); University of Sydney; Sydney; Australia

PubMed=19935656; DOI=10.1038/nbt.1587
Henson J.D., Cao Y., Huschtscha L.I., Chang A.C.-M., Au A.Y.M., Pickett H.A., Reddel R.R.
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
Nat. Biotechnol. 27:1181-1185(2009)

PubMed=23257959; DOI=10.4161/epi.23366; PMCID=PMC3549877
Heyn H., Moran S., Esteller M.
Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford progeria and Werner syndrome.
Epigenetics 8:28-33(2013)