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Cellosaurus PC-9/f9 (CVCL_U150)

[Text version]
Cell line name PC-9/f9
Synonyms PC-9-f9; PC9/f9
Accession CVCL_U150
Resource Identification Initiative To cite this cell line use: PC-9/f9 (RRID:CVCL_U150)
Comments Population: Chinese; Han and Japanese.
Characteristics: Highly metastatic. Established after nine passages of the parent cell line in nude mice (PubMed=11078804).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Children:
CVCL_U149 (PC-9/f14)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=11078804; DOI=10.3892/ijo.17.6.1187
Takenaka K., Shibuya M., Takeda Y., Hibino S., Gemma A., Ono Y., Kudoh S.
Altered expression and function of beta1 integrins in a highly metastatic human lung adenocarcinoma cell line.
Int. J. Oncol. 17:1187-1194(2000)

PubMed=11506965; DOI=10.1016/S0959-8049(01)00154-X
Gemma A., Takenaka K., Hosoya Y., Matuda K., Seike M., Kurimoto F., Ono Y., Uematsu K., Takeda Y., Hibino S., Yoshimura A., Shibuya M., Kudoh S.
Altered expression of several genes in highly metastatic subpopulations of a human pulmonary adenocarcinoma cell line.
Eur. J. Cancer 37:1554-1561(2001)

PubMed=12696064; DOI=10.1002/gcc.10205
Yoshimura A., Gemma A., Hosoya Y., Komaki E., Hosomi Y., Okano T., Takenaka K., Matuda K., Seike M., Uematsu K., Hibino S., Shibuya M., Yamada T., Hirohashi S., Kudoh S.
Increased expression of the LGALS3 (galectin 3) gene in human non-small-cell lung cancer.
Genes Chromosomes Cancer 37:159-164(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_U150
Encyclopedic resources Wikidata; Q54938493
Polymorphism and mutation databases Cosmic; 915330
Entry history
Entry creation03-Feb-2014
Last entry update10-Sep-2024
Version number17