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Cellosaurus 253G4 (CVCL_T792)

[Text version]
Cell line name 253G4
Synonyms 253-G4; 253G-4; HPS4291
Accession CVCL_T792
Resource Identification Initiative To cite this cell line use: 253G4 (RRID:CVCL_T792)
Comments From: Center for iPS Cell Research and Application, Kyoto University; Kyoto; Japan.
Population: Caucasian.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DP59 (HDF1388)
Sex of cell Female
Age at sampling 36Y
Category Induced pluripotent stem cell
Publications

PubMed=18059259; DOI=10.1038/nbt1374
Nakagawa M., Koyanagi M., Tanabe K., Takahashi K., Ichisaka T., Aoi T., Okita K., Mochiduki Y., Takizawa N., Yamanaka S.
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.
Nat. Biotechnol. 26:101-106(2008)

PubMed=21098095; DOI=10.1084/jem.20100844; PMCID=PMC3005234
Takayama N., Nishimura S., Nakamura S., Shimizu T., Ohnishi R., Endo H., Yamaguchi T., Otsu M., Nishimura K., Nakanishi M., Sawaguchi A., Nagai R., Takahashi K., Yamanaka S., Nakauchi H., Eto K.
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells.
J. Exp. Med. 207:2817-2830(2010)

PubMed=21460823; DOI=10.1038/nmeth.1591
Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S., Hong H.-J., Nakagawa M., Tanabe K., Tezuka K.-i., Shibata T., Kunisada T., Takahashi M., Takahashi J., Saji H., Yamanaka S.
A more efficient method to generate integration-free human iPS cells.
Nat. Methods 8:409-412(2011)

PubMed=22802639; DOI=10.1073/pnas.1209979109; PMCID=PMC3411998
Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N., Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012)

PubMed=24259714; DOI=10.1073/pnas.1319061110; PMCID=PMC3870695
Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H., Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N., Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J., Yamanaka S.
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells.
Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013)

PubMed=27476965; DOI=10.1016/j.stem.2016.06.019
Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M., Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M., Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A., Yamanaka S., Yoshida Y.
Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity.
Cell Stem Cell 19:341-354(2016)

Cross-references
Cell line collections (Providers) RCB; HPS4291
Cell line databases/resources SKIP; SKIP001451
Encyclopedic resources Wikidata; Q54583651
Gene expression databases GEO; GSM1040252
GEO; GSM1040322
GEO; GSM1489220
GEO; GSM1489250
GEO; GSM1489426
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number11