ID   253G4
AC   CVCL_T792
SY   253-G4; 253G-4; HPS4291
DR   GEO; GSM1040252
DR   GEO; GSM1040322
DR   GEO; GSM1489220
DR   GEO; GSM1489250
DR   GEO; GSM1489426
DR   RCB; HPS4291
DR   SKIP; SKIP001451
DR   Wikidata; Q54583651
RX   PubMed=18059259;
RX   PubMed=21098095;
RX   PubMed=21460823;
RX   PubMed=22802639;
RX   PubMed=24259714;
RX   PubMed=27476965;
CC   From: Center for iPS Cell Research and Application, Kyoto University; Kyoto; Japan.
CC   Population: Caucasian.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_DP59 ! HDF1388
SX   Female
AG   36Y
CA   Induced pluripotent stem cell
DT   Created: 03-02-14; Last updated: 29-06-23; Version: 11
//
RX   PubMed=18059259; DOI=10.1038/nbt1374;
RA   Nakagawa M., Koyanagi M., Tanabe K., Takahashi K., Ichisaka T.,
RA   Aoi T., Okita K., Mochiduki Y., Takizawa N., Yamanaka S.;
RT   "Generation of induced pluripotent stem cells without Myc from mouse
RT   and human fibroblasts.";
RL   Nat. Biotechnol. 26:101-106(2008).
//
RX   PubMed=21098095; DOI=10.1084/jem.20100844; PMCID=PMC3005234;
RA   Takayama N., Nishimura S., Nakamura S., Shimizu T., Ohnishi R.,
RA   Endo H., Yamaguchi T., Otsu M., Nishimura K., Nakanishi M.,
RA   Sawaguchi A., Nagai R., Takahashi K., Yamanaka S., Nakauchi H.,
RA   Eto K.;
RT   "Transient activation of c-MYC expression is critical for efficient
RT   platelet generation from human induced pluripotent stem cells.";
RL   J. Exp. Med. 207:2817-2830(2010).
//
RX   PubMed=21460823; DOI=10.1038/nmeth.1591;
RA   Okita K., Matsumura Y., Sato Y., Okada A., Morizane A., Okamoto S.,
RA   Hong H.-J., Nakagawa M., Tanabe K., Tezuka K.-i., Shibata T.,
RA   Kunisada T., Takahashi M., Takahashi J., Saji H., Yamanaka S.;
RT   "A more efficient method to generate integration-free human iPS
RT   cells.";
RL   Nat. Methods 8:409-412(2011).
//
RX   PubMed=22802639; DOI=10.1073/pnas.1209979109; PMCID=PMC3411998;
RA   Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N.,
RA   Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.;
RT   "Donor-dependent variations in hepatic differentiation from
RT   human-induced pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012).
//
RX   PubMed=24259714; DOI=10.1073/pnas.1319061110; PMCID=PMC3870695;
RA   Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H.,
RA   Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N.,
RA   Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J.,
RA   Yamanaka S.;
RT   "Differentiation-defective phenotypes revealed by large-scale analyses
RT   of human pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013).
//
RX   PubMed=27476965; DOI=10.1016/j.stem.2016.06.019;
RA   Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M.,
RA   Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M.,
RA   Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A.,
RA   Yamanaka S., Yoshida Y.;
RT   "Epigenetic variation between human induced pluripotent stem cell
RT   lines is an indicator of differentiation capacity.";
RL   Cell Stem Cell 19:341-354(2016).
//