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Cellosaurus M000921 (CVCL_S808)

[Text version]
Cell line name M000921
Synonyms M00921
Accession CVCL_S808
Resource Identification Initiative To cite this cell line use: M000921 (RRID:CVCL_S808)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: URPP Biobank, University of Zurich; Zurich; Switzerland.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Age/sex of donor and metastatic site from personal communication of URPP Biobank.
Derived from site: Metastatic; Epigastrium; UBERON=UBERON_0035276.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=16827748; DepMap).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=22336146; DOI=10.1111/j.1755-148X.2012.00986.x
Widmer D.S., Cheng P.F., Eichhoff O.M., Belloni B.C., Zipser M.C., Schlegel N.C., Javelaud D., Mauviel A., Dummer R., Hoek K.S.
Systematic classification of melanoma cells by phenotype-specific gene expression mapping.
Pigment Cell Melanoma Res. 25:343-353(2012)

PubMed=24581590; DOI=10.1016/j.jdermsci.2014.01.006
Gehrke S., Otsuka A., Huber R., Meier B., Kistowska M., Fenini G., Cheng P., Dummer R., Kerl K., Contassot E., French L.E.
Metastatic melanoma cell lines do not secrete IL-1beta but promote IL-1beta production from macrophages.
J. Dermatol. Sci. 74:167-169(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S808
Cell_Model_Passport; SIDM00178
DepMap; ACH-002386
IGRhCellID; M000921
Chemistry resources PharmacoDB; M00921_876_2019
Encyclopedic resources Wikidata; Q54903405
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM108381
GEO; GSM108391
GEO; GSM433916
Polymorphism and mutation databases Cosmic; 1723793
Progenetix; CVCL_S808
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number19