ID   M000921
AC   CVCL_S808
SY   M00921
DR   ArrayExpress; E-MTAB-3610
DR   cancercelllines; CVCL_S808
DR   Cell_Model_Passport; SIDM00178
DR   Cosmic; 1723793
DR   DepMap; ACH-002386
DR   EGA; EGAS00001000978
DR   GEO; GSM108381
DR   GEO; GSM108391
DR   GEO; GSM433916
DR   IGRhCellID; M000921
DR   PharmacoDB; M00921_876_2019
DR   Progenetix; CVCL_S808
DR   Wikidata; Q54903405
RX   PubMed=16827748;
RX   PubMed=22336146;
RX   PubMed=24581590;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   From: URPP Biobank, University of Zurich; Zurich; Switzerland.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=16827748; DepMap=ACH-002386).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: Age/sex of donor and metastatic site from personal communication of URPP Biobank.
CC   Derived from site: Metastatic; Epigastrium; UBERON=UBERON_0035276.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 02-05-24; Version: 20
//
RX   PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x;
RA   Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R.,
RA   Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D.,
RA   Dummer R.;
RT   "Metastatic potential of melanomas defined by specific gene expression
RT   profiles with no BRAF signature.";
RL   Pigment Cell Res. 19:290-302(2006).
//
RX   PubMed=22336146; DOI=10.1111/j.1755-148X.2012.00986.x;
RA   Widmer D.S., Cheng P.F., Eichhoff O.M., Belloni B.C., Zipser M.C.,
RA   Schlegel N.C., Javelaud D., Mauviel A., Dummer R., Hoek K.S.;
RT   "Systematic classification of melanoma cells by phenotype-specific
RT   gene expression mapping.";
RL   Pigment Cell Melanoma Res. 25:343-353(2012).
//
RX   PubMed=24581590; DOI=10.1016/j.jdermsci.2014.01.006;
RA   Gehrke S., Otsuka A., Huber R., Meier B., Kistowska M., Fenini G.,
RA   Cheng P., Dummer R., Kerl K., Contassot E., French L.E.;
RT   "Metastatic melanoma cell lines do not secrete IL-1beta but promote
RT   IL-1beta production from macrophages.";
RL   J. Dermatol. Sci. 74:167-169(2014).
//