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Cellosaurus ORL-115 (CVCL_S690)

[Text version]
Cell line name ORL-115
Synonyms ORL-115T; 115T
Accession CVCL_S690
Resource Identification Initiative To cite this cell line use: ORL-115 (RRID:CVCL_S690)
Comments Population: Indian.
Microsatellite instability: Stable (MSS) (PubMed=17273794).
Omics: CRISPR phenotypic screen.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
Sequence variations
Disease Gingival squamous cell carcinoma (NCIt: C129857)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX
CSF1PO11
D2S133818,23
D3S135816
D5S81812
D7S8208,10
D8S117910,13
D13S3178,12
D16S53911
D18S5114
D19S43314
D21S1129,30
FGA20,23
TH019
TPOX9,10
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=17273794; DOI=10.3892/ijmm.19.3.453
Hamid S., Lim K.P., Zain R.B., Ismail S.M., Lau S.H., Mustafa W.M.W., Abraham M.T., Nam N.A., Teo S.-H., Cheong S.-C.
Establishment and characterization of Asian oral cancer cell lines as in vitro models to study a disease prevalent in Asia.
Int. J. Mol. Med. 19:453-460(2007)

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:E80229-E80229(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Chai A.W.-Y., Yee P.-S., Price S., Yee S.-M., Lee H.-M., Tiong V.K.H., Goncalves E., Behan F.M., Bateson J., Gilbert J.G.R., Tan A.-C., McDermott U., Garnett M.J., Cheong S.-C.
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S690
Cell_Model_Passport; SIDM02007
CRISP screens repositories BioGRID_ORCS_Cell_line; 1271
Encyclopedic resources Wikidata; Q54936490
Polymorphism and mutation databases Cosmic; 2531643
Cosmic; 2559735
IARC_TP53; 25070
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number16