Cellosaurus HEp2-Mx2/EGFP L1D7 (CVCL_RX04)
| Cell line name | HEp2-Mx2/EGFP L1D7 |
|---|---|
| Synonyms | HEp L1D7 |
| Accession | CVCL_RX04 |
| Resource Identification Initiative | To cite this cell line use: HEp2-Mx2/EGFP L1D7 (RRID:CVCL_RX04) |
| Comments | Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative. Population: African American. Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency. Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter. Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_1906 (HEp-2) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=22373148; DOI=10.1186/1753-6561-5-S8-P4; PMCID=PMC3284889 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54882750 |
| Entry history | |
| Entry creation | 05-Mar-2018 |
| Last entry update | 10-Sep-2024 |
| Version number | 8 |