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Cellosaurus U2OS GFP-LMNB1 (CVCL_RQ92)

[Text version]
Cell line name U2OS GFP-LMNB1
Accession CVCL_RQ92
Resource Identification Initiative To cite this cell line use: U2OS GFP-LMNB1 (RRID:CVCL_RQ92)
Comments Population: Caucasian.
Characteristics: Using ZFN a TagGFP2 construct was integrated at the N-terminus of the LMNB1 gene (Sigma-Aldrich=CLL1033).
Genetic integration: Method=ZFN; Gene=FPbase; GJETS; TagGFP2 (Note=Green fluorescent protein derived from Aequorea macrodactyla GFP).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Sigma-Aldrich; CLL1033
Encyclopedic resources Wikidata; Q54973658
Entry history
Entry creation05-Mar-2018
Last entry update10-Sep-2024
Version number8