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Cellosaurus U2OS GFP-NUP98 (CVCL_RQ88)

[Text version]
Cell line name U2OS GFP-NUP98
Accession CVCL_RQ88
Resource Identification Initiative To cite this cell line use: U2OS GFP-NUP98 (RRID:CVCL_RQ88)
Comments Population: Caucasian.
Characteristics: Using ZFN a 3XFLAG-TagGFP2 construct was integrated at the N-terminus of the NUP98 gene (Sigma-Aldrich=CLL1136).
Genetic integration: Method=ZFN; Gene=FPbase; GJETS; TagGFP2 (Note=Green fluorescent protein derived from Aequorea macrodactyla GFP).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Sigma-Aldrich; CLL1136
Encyclopedic resources Wikidata; Q54973659
Entry history
Entry creation05-Mar-2018
Last entry update10-Sep-2024
Version number8