Cellosaurus cell line SU223-A4 (CVCL

Cross-references
Cell line name	SU223-A4
Accession	CVCL_RK84
Resource Identification Initiative	To cite this cell line use: SU223-A4 (RRID:CVCL_RK84)
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Unspecified; Note=Somatic (PubMed=28089908). Mutation; HGNC; HGNC:10729; SEMA4A; Simple; p.Tyr589His (c.1765T>C); ClinVar=VCV001418371; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
Disease	Adult acute myeloid leukemia (NCIt: C9154) Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_RK83 ! SU223-A2 CVCL_RK85 ! SU223-A7 CVCL_RK86 ! SU223-B3 CVCL_RK87 ! SU223-B5 CVCL_RK88 ! SU223T-4 CVCL_RK89 ! SU223T-5 CVCL_RK90 ! SU223T-6
Sex of cell	Female
Age at sampling	20Y
Category	Induced pluripotent stem cell
Publications	PubMed=28089908; DOI=10.1016/j.stem.2016.11.018; PMCID=PMC5508733 Chao M.P., Gentles A.J., Chatterjee S., Lan F., Reinisch A., Corces M.R., Xavy S., Shen J.-F., Haag D., Chanda S., Sinha R., Morganti R.M., Nishimura T., Ameen M., Wu H.-D., Wernig M., Wu J.C., Majeti R. Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease. Cell Stem Cell 20:329-344.e7(2017)
Cell line databases/resources	SKIP; SKIP001720
Encyclopedic resources	Wikidata; Q54970759
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	8