ID   SU223-A4
AC   CVCL_RK84
DR   SKIP; SKIP001720
DR   Wikidata; Q54970759
RX   PubMed=28089908;
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
CC   Sequence variation: Mutation; HGNC; HGNC:10729; SEMA4A; Simple; p.Tyr589His (c.1765T>C); ClinVar=VCV001418371; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_RK83 ! SU223-A2
OI   CVCL_RK85 ! SU223-A7
OI   CVCL_RK86 ! SU223-B3
OI   CVCL_RK87 ! SU223-B5
OI   CVCL_RK88 ! SU223T-4
OI   CVCL_RK89 ! SU223T-5
OI   CVCL_RK90 ! SU223T-6
SX   Female
AG   20Y
CA   Induced pluripotent stem cell
DT   Created: 05-03-18; Last updated: 19-12-24; Version: 8
//
RX   PubMed=28089908; DOI=10.1016/j.stem.2016.11.018; PMCID=PMC5508733;
RA   Chao M.P., Gentles A.J., Chatterjee S., Lan F., Reinisch A.,
RA   Corces M.R., Xavy S., Shen J.-F., Haag D., Chanda S., Sinha R.,
RA   Morganti R.M., Nishimura T., Ameen M., Wu H.-D., Wernig M., Wu J.C.,
RA   Majeti R.;
RT   "Human AML-iPSCs reacquire leukemic properties after differentiation
RT   and model clonal variation of disease.";
RL   Cell Stem Cell 20:329-344.e7(2017).
//