| Cell line name |
SU042-5 |
|---|
| Accession |
CVCL_RK77 |
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| Resource Identification Initiative |
To cite this cell line use: SU042-5 (RRID:CVCL_RK77) |
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| Sequence variations |
- Mutation; HGNC; HGNC:795; ATM; Simple; p.Val2193Ile (c.6577G>A); ClinVar=VCV000231987; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
- Mutation; HGNC; HGNC:2978; DNMT3A; Simple; p.Ser837Ter (c.2510C>G); Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
- Mutation; HGNC; HGNC:30045; SMG1; Simple; p.Leu250Val; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
- Mutation; HGNC; HGNC:17575; SPEN; Simple; p.Thr1673Ser; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
|
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| Disease |
Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Originate from same individual |
CVCL_RK73 ! SU042-1
CVCL_RK74 ! SU042-2
CVCL_RK75 ! SU042-3
CVCL_RK76 ! SU042-4
CVCL_RK78 ! SU42T-2
CVCL_RK79 ! SU42T-4
CVCL_RK80 ! SU42T-5 |
|---|
| Sex of cell |
Female |
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| Age at sampling |
61Y |
|---|
| Category |
Induced pluripotent stem cell |
|---|
| Publications | PubMed=28089908; DOI=10.1016/j.stem.2016.11.018; PMCID=PMC5508733
Chao M.P., Gentles A.J., Chatterjee S., Lan F., Reinisch A., Corces M.R., Xavy S., Shen J.-F., Haag D., Chanda S., Sinha R., Morganti R.M., Nishimura T., Ameen M., Wu H.-D., Wernig M., Wu J.C., Majeti R.
Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease.
Cell Stem Cell 20:329-344.e7(2017) |
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| Cross-references |
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| Cell line databases/resources |
SKIP; SKIP001718
|
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| Encyclopedic resources |
Wikidata; Q54970754
|
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| Entry history |
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| Entry creation | 05-Mar-2018 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 9 |
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