Cellosaurus cell line RIT-2 (CVCL

Cross-references
Cell line name	RIT-2
Synonyms	RIT 2; Radiation-Induced Tumor-2
Accession	CVCL_RK39
Resource Identification Initiative	To cite this cell line use: RIT-2 (RRID:CVCL_RK39)
Comments	Donor information: Established from a patient originally treated by radiation therapy for a breast carcinoma (PubMed=2253180).
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified (PubMed=1933904).
Disease	Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	29Y
Category	Cancer cell line
Publications	PubMed=2253180; DOI=10.1016/0165-4608(90)90246-7 Cowan J.M., Beckett M.A., Tarbell N.J., Weichselbaum R.R. Symmetrical chromosome rearrangements in cell lines established from human radiation-induced sarcomas. Cancer Genet. Cytogenet. 50:125-137(1990) PubMed=1933904 Brachman D.G., Hallahan D.E., Beckett M.A., Yandell D.W., Weichselbaum R.R. p53 gene mutations and abnormal retinoblastoma protein in radiation-induced human sarcomas. Cancer Res. 51:6393-6396(1991)
Cell line databases/resources	cancercelllines; CVCL_RK39
Encyclopedic resources	Wikidata; Q54950501
Polymorphism and mutation databases	IARC_TP53; 691
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	8