ID   RIT-2
AC   CVCL_RK39
SY   RIT 2; Radiation-Induced Tumor-2
DR   cancercelllines; CVCL_RK39
DR   IARC_TP53; 691
DR   Wikidata; Q54950501
RX   PubMed=1933904;
RX   PubMed=2253180;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified (PubMed=1933904).
CC   Donor information: Established from a patient originally treated by radiation therapy for a breast carcinoma (PubMed=2253180).
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   29Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 19-12-24; Version: 8
//
RX   PubMed=1933904;
RA   Brachman D.G., Hallahan D.E., Beckett M.A., Yandell D.W.,
RA   Weichselbaum R.R.;
RT   "p53 gene mutations and abnormal retinoblastoma protein in
RT   radiation-induced human sarcomas.";
RL   Cancer Res. 51:6393-6396(1991).
//
RX   PubMed=2253180; DOI=10.1016/0165-4608(90)90246-7;
RA   Cowan J.M., Beckett M.A., Tarbell N.J., Weichselbaum R.R.;
RT   "Symmetrical chromosome rearrangements in cell lines established from
RT   human radiation-induced sarcomas.";
RL   Cancer Genet. Cytogenet. 50:125-137(1990).
//