• Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:18874; LAT; Simple; g.237C>T; Zygosity=Heterozygous (PubMed=27278128; PubMed=33562083).
  
• Mutation; HGNC; HGNC:18874; LAT; Simple; p.Thr56Met (c.167C>T); ClinVar=VCV001493770; Zygosity=Heterozygous (PubMed=27278128; PubMed=33562083).
  
• Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11491; SYK; Simple; p.Met34Hisfs*3 (c.98_99insG); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
  

PubMed=3263650; DOI=10.1073/pnas.85.22.8613; PMCID=PMC282509
Goldsmith M.A., Dazin P.F., Weiss A.
At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor.
Proc. Natl. Acad. Sci. U.S.A. 85:8613-8617(1988)

PubMed=9846483; DOI=10.1016/S1074-7613(00)80659-7
Finco T.S., Kadlecek T., Zhang W.-G., Samelson L.E., Weiss A.
LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway.
Immunity 9:617-626(1998)

PubMed=27278128; DOI=10.1038/gene.2016.25; PMCID=PMC4972999
Marek-Bukowiec K., Aguado E., Miazek A.
Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription.
Genes Immun. 17:313-320(2016)

PubMed=33562083; DOI=10.3390/cells10020343; PMCID=PMC7915312
Vico-Barranco I., de Arbulo-Echevarria M.M., Serrano-Garcia I., Perez-Linaza A., Miranda-Sayago J.M., Miazek A., Narbona-Sanchez I., Aguado E.
A novel, LAT/Lck double deficient T cell subline J.CaM1.7 for combined analysis of early TCR signaling.
Cells 10:343.1-343.20(2021)