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Cellosaurus VA-ES-BJ BAF47 (CVCL_QW58)

[Text version]
Cell line name VA-ES-BJ BAF47
Synonyms VA-ES-BJ_BAF47; VAESBJ_BAF47
Accession CVCL_QW58
Resource Identification Initiative To cite this cell line use: VA-ES-BJ BAF47 (RRID:CVCL_QW58)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11103; SMARCB1.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Homozygous (from parent cell line).
Disease Epithelioid sarcoma (NCIt: C3714)
Epithelioid sarcoma (ORDO: Orphanet_293202)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1785 (VA-ES-BJ)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080
Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C.
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Nat. Genet. 49:1613-1623(2017)

Cross-references
Encyclopedic resources Wikidata; Q54992644
Gene expression databases GEO; GSM2409700
GEO; GSM2409701
GEO; GSM2409702
GEO; GSM2409703
GEO; GSM2409704
GEO; GSM2409705
GEO; GSM2787359
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number11