Cellosaurus cell line TTC-1240 BAF47 (CVCL

Cellosaurus TTC-1240 BAF47 (CVCL_QW57)

Cross-references
Cell line name	TTC-1240 BAF47
Synonyms	TTC1240 BAF47; TTC1240_BAF47
Accession	CVCL_QW57
Resource Identification Initiative	To cite this cell line use: TTC-1240 BAF47 (RRID:CVCL_QW57)
Comments	Characteristics: Transfection of SMARCB1 rescues the phenotype of the parent cell line which has a deleterious mutation in that gene. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11103; SMARCB1. Omics: H3K27ac ChIP-seq epigenome analysis. Omics: H3K27me3 ChIP-seq epigenome analysis. Omics: H3K4me1 ChIP-seq epigenome analysis. Omics: H3K4me3 ChIP-seq epigenome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Disease	Rhabdoid tumor of the kidney (NCIt: C8715) Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_8002 (TTC-1240)
Sex of cell	Female
Age at sampling	9M
Category	Cancer cell line
Publications	PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080 Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C. SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters. Nat. Genet. 49:1613-1623(2017)
Encyclopedic resources	Wikidata; Q54973231
Gene expression databases	GEO; GSM2409676 GEO; GSM2409677 GEO; GSM2409678 GEO; GSM2409679 GEO; GSM2409680 GEO; GSM2409681 GEO; GSM2409708 GEO; GSM2495987 GEO; GSM2495989 GEO; GSM2787355
Entry history
Entry creation	15-Nov-2017
Last entry update	19-Dec-2024
Version number	8