Cellosaurus logo
expasy logo

Cellosaurus Cheptage (CVCL_M652)

[Text version]
Cell line name Cheptage
Synonyms Chep-BL; CHEP-BL; CHEP BL; Chep BL; CHEP; Chep
Accession CVCL_M652
Resource Identification Initiative To cite this cell line use: Cheptage (RRID:CVCL_M652)
Comments Population: African; Kenyan.
Virology: Contains a complete EBV genome (strain Cheptage) which has been sequenced (PubMed=25787276).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, mandible; UBERON=UBERON_0001684.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 10Y
Category Cancer cell line
Publications

PubMed=2985508; DOI=10.1002/ijc.2910350404
Rowe M., Rooney C.M., Rickinson A.B., Lenoir G.M., Rupani H., Moss D.J., Stein H., Epstein M.A.
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=2943927; DOI=10.1093/jnci/77.3.681
Rooney C.M., Gregory C.D., Rowe M., Finerty S., Edwards C.F., Rupani H., Rickinson A.B.
Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells and of derived tumor cell lines.
J. Natl. Cancer Inst. 77:681-687(1986)

PubMed=2824665; DOI=10.1099/0022-1317-68-11-2853
Young L.S., Yao Q.-Y., Rooney C.M., Sculley T.B., Moss D.J., Rupani H., Laux G., Bornkamm G.-W., Rickinson A.B.
New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas.
J. Gen. Virol. 68:2853-2862(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Gregory C.D., Murray R.J., Edwards C.F., Rickinson A.B.
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

PubMed=25787276; DOI=10.1128/JVI.03614-14; PMCID=PMC4442510
Palser A.L., Grayson N.E., White R.E., Corton C., Correia S., Ba Abdullah M.M., Watson S.J., Cotten M., Arrand J.R., Murray P.G., Allday M.J., Rickinson A.B., Young L.S., Farrell P.J., Kellam P.
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.
J. Virol. 89:5222-5237(2015)

PubMed=28960205; DOI=10.1038/cdd.2017.150; PMCID=PMC5762840
Fitzsimmons L., Boyce A.J., Wei W.-B., Chang C., Croom-Carter D.S.G., Tierney R.J., Herold M.J., Bell A.I., Strasser A., Kelly G.L., Rowe M.
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Cell Death Differ. 25:241-254(2018)

Cross-references
Encyclopedic resources Wikidata; Q54811845
Entry history
Entry creation05-Nov-2013
Last entry update02-May-2024
Version number14