Cellosaurus logo
expasy logo

Cellosaurus BL-21 (CVCL_M639)

[Text version]
Cell line name BL-21
Synonyms BL21; BL 21; IARC/BL21; IARC/BL 21; IARC-BL21; IARC BL21; IARC BL 21
Accession CVCL_M639
Resource Identification Initiative To cite this cell line use: BL-21 (RRID:CVCL_M639)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Algerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Cerebrospinal fluid; UBERON=UBERON_0001359.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_M555 ! BL-7
CVCL_C138 ! BL-17
Sex of cell Male
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=6806672; DOI=10.1038/298474a0
Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.
Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma.
Nature 298:474-476(1982)

PubMed=6441706; DOI=10.1002/j.1460-2075.1984.tb02239.x; PMCID=PMC557796
Rappold G.A., Hameister H., Cremer T., Adolph S., Henglein B., Freese U.-K., Lenoir G.M., Bornkamm G.-W.
c-myc and immunoglobulin kappa light chain constant genes are on the 8q+ chromosome of three Burkitt lymphoma lines with t(2;8) translocations.
EMBO J. 3:2951-2955(1984)

PubMed=6592381; DOI=10.1093/jnci/73.4.841
Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F., Lenoir G.M.
Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with the ethnic origin.
J. Natl. Cancer Inst. 73:841-847(1984)

PubMed=3905596
Favrot M.-C., Philip I., Philip T., Cabrillat H., Pinatel C., Dore J.-F., Lenoir G.M.
Immunophenotypic classification of 28 Burkitt cell lines with monoclonal antibodies and reagent selection for bone-marrow purging.
IARC Sci. Publ. 60:447-452(1985)

PubMed=3934070
Lenoir G.M., Vuillaume M., Bonnardel C.
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M., Manel A.-M., Vincent C., Bryon P.-A.
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2470097; DOI=10.1073/pnas.86.9.3257; PMCID=PMC287109
Shtivelman E., Henglein B., Groitl P., Lipp M., Bishop J.M.
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.
Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989)

PubMed=8108117
Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=22120970; DOI=10.1002/gcc.21915
Kroenlein H., Schwartz S., Reinhardt R., Rieder H., Molkentin M., Gokbuget N., Hoelzer D., Thiel E., Burmeister T.
Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade lymphoma/leukemia by long-distance inverse PCR.
Genes Chromosomes Cancer 51:290-299(2012)

Cross-references
Encyclopedic resources Wikidata; Q54797123
Polymorphism and mutation databases Cosmic; 2804865
Entry history
Entry creation05-Nov-2013
Last entry update02-May-2024
Version number16