ID   BL-21
AC   CVCL_M639
SY   BL21; BL 21; IARC/BL21; IARC/BL 21; IARC-BL21; IARC BL21; IARC BL 21
DR   Cosmic; 2804865
DR   Wikidata; Q54797123
RX   PubMed=2470097;
RX   PubMed=3027441;
RX   PubMed=3905596;
RX   PubMed=3934070;
RX   PubMed=6441706;
RX   PubMed=6592381;
RX   PubMed=6806672;
RX   PubMed=8108117;
RX   PubMed=22120970;
CC   From: International Agency of Research on Cancer (IARC); Lyon; France.
CC   Population: Algerian.
CC   Sequence variation: Gene fusion; HGNC; 5715; IGK + HGNC; 7553; MYC; Name(s)=MYC-IGK (PubMed=6441706; PubMed=6806672; PubMed=22120970).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Cerebrospinal fluid; UBERON=UBERON_0001359.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_M555 ! BL-7
OI   CVCL_C138 ! BL-17
SX   Male
AG   9Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 02-05-24; Version: 16
//
RX   PubMed=2470097; DOI=10.1073/pnas.86.9.3257; PMCID=PMC287109;
RA   Shtivelman E., Henglein B., Groitl P., Lipp M., Bishop J.M.;
RT   "Identification of a human transcription unit affected by the variant
RT   chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989).
//
RX   PubMed=3027441; DOI=10.1093/jnci/78.2.235;
RA   Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M.,
RA   Manel A.-M., Vincent C., Bryon P.-A.;
RT   "B-cell maturation stages of Burkitt's lymphoma cell lines according
RT   to Epstein-Barr virus status and type of chromosome translocation.";
RL   J. Natl. Cancer Inst. 78:235-242(1987).
//
RX   PubMed=3905596;
RA   Favrot M.-C., Philip I., Philip T., Cabrillat H., Pinatel C.,
RA   Dore J.-F., Lenoir G.M.;
RT   "Immunophenotypic classification of 28 Burkitt cell lines with
RT   monoclonal antibodies and reagent selection for bone-marrow purging.";
RL   IARC Sci. Publ. 60:447-452(1985).
//
RX   PubMed=3934070;
RA   Lenoir G.M., Vuillaume M., Bonnardel C.;
RT   "The use of lymphomatous and lymphoblastoid cell lines in the study of
RT   Burkitt's lymphoma.";
RL   IARC Sci. Publ. 60:309-318(1985).
//
RX   PubMed=6441706; DOI=10.1002/j.1460-2075.1984.tb02239.x; PMCID=PMC557796;
RA   Rappold G.A., Hameister H., Cremer T., Adolph S., Henglein B.,
RA   Freese U.-K., Lenoir G.M., Bornkamm G.-W.;
RT   "c-myc and immunoglobulin kappa light chain constant genes are on the
RT   8q+ chromosome of three Burkitt lymphoma lines with t(2;8)
RT   translocations.";
RL   EMBO J. 3:2951-2955(1984).
//
RX   PubMed=6592381; DOI=10.1093/jnci/73.4.841;
RA   Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F.,
RA   Lenoir G.M.;
RT   "Distinct reactivity of Burkitt's lymphoma cell lines with eight
RT   monoclonal antibodies correlated with the ethnic origin.";
RL   J. Natl. Cancer Inst. 73:841-847(1984).
//
RX   PubMed=6806672; DOI=10.1038/298474a0;
RA   Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.;
RT   "Correlation between immunoglobulin light chain expression and variant
RT   translocation in Burkitt's lymphoma.";
RL   Nature 298:474-476(1982).
//
RX   PubMed=8108117;
RA   Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.;
RT   "Ongoing mutations in the N-terminal domain of c-Myc affect
RT   transactivation in Burkitt's lymphoma cell lines.";
RL   Oncogene 9:759-763(1994).
//
RX   PubMed=22120970; DOI=10.1002/gcc.21915;
RA   Kroenlein H., Schwartz S., Reinhardt R., Rieder H., Molkentin M.,
RA   Gokbuget N., Hoelzer D., Thiel E., Burmeister T.;
RT   "Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade
RT   lymphoma/leukemia by long-distance inverse PCR.";
RL   Genes Chromosomes Cancer 51:290-299(2012).
//