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Cellosaurus HEK (CVCL_M624)

[Text version]
Cell line name HEK
Synonyms Human Embryonic Kidney; HEK-1; HEK-RLV
Accession CVCL_M624
Resource Identification Initiative To cite this cell line use: HEK (RRID:CVCL_M624)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=4864103; PubMed=20143388). Originally thought to originate from an embryonic kidney.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00063.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Caution: Not to be confused with cell line HEK293 (Cellosaurus=CVCL_0045).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

Gartler S.M.
Genetic markers as tracers in cell culture.
Natl. Cancer Inst. Monogr. 26:167-195(1967)

Mayyasi S.A., Traul K.A., Garon C.E., Wright B., Maywood N.J.
Antigenics characteristics of Rauscher virus cultivated in human embryonic kidney cells.
Proc. Am. Assoc. Cancer Res. 11:54-54(1970)

PubMed=4621398; DOI=10.3181/00379727-139-36065
Traul K.A., Mayyasi S.A., Garon C.E., Schidlovsky G., Bulfone L.M.
Antigenic comparison of Rauscher murine leukemia virus cultivated in human embryo and mouse cells.
Proc. Soc. Exp. Biol. Med. 139:10-14(1972)

Eckner R.J., Priori E.S., Mirand E.A., Dmochowski L.
Studies on the biological and antigenic properties of ESP-1 type C virus particles.
Cancer Res. 34:2521-2529(1974)

PubMed=4469665; DOI=10.1126/science.184.4141.1093
Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.
Banded marker chromosomes as indicators of intraspecies cellular contamination.
Science 184:1093-1096(1974)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151703
Encyclopedic resources Wikidata; Q54882276
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number17