Cellosaurus cell line AMU-ML1 (CVCL

Cellosaurus AMU-ML1 (CVCL_M583)

Cross-references
Cell line name	AMU-ML1
Accession	CVCL_M583
Resource Identification Initiative	To cite this cell line use: AMU-ML1 (RRID:CVCL_M583)
Comments	Population: Japanese. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene fusion; HGNC; HGNC:1001; BCL6 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL6 (DOI=10.1182/blood.V118.21.5210.5210). Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5853; IGL; Name(s)=IGL-BCL2 (DOI=10.1182/blood.V118.21.5210.5210). Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (DOI=10.1182/blood.V118.21.5210.5210).
Disease	High grade B-cell lymphoma with MYC, BCL2, and BCL6 rearrangements (NCIt: C131913) High grade B-cell lymphoma with MYC and/or BCL2 and/or BCL6 rearrangement (ORDO: Orphanet_480541)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	60Y
Category	Cancer cell line
Publications	DOI=10.1182/blood.V118.21.5210.5210 Tsunekawa N., Hanamura I., Yamamoto H., Nagoshi H., Wakabayashi M., Sakamoto N., Horio T., Gotoh M., Mizuno S., Takahashi M., Suganuma K., Goto M., Hiramatsu A., Watarai M., Shikami M., Imamura A., Mihara H., Taki T., Taniwaki M., Miwa H., Nitta M. Establishment and characterization of a novel human cell line of triple hit lymphoma, AMU-ML1, carrying t(2;18)(p11.2;q21) and t(3;8;14)(q27;q24;q32) that involve BCL2, BCL6 and MYC. Blood 118 Suppl. 1:5210a-5210a(2011)
Encyclopedic resources	Wikidata; Q54749845
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	14