ID   AMU-ML1
AC   CVCL_M583
DR   Wikidata; Q54749845
RX   DOI=10.1182/blood.V118.21.5210.5210;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:1001; BCL6 + HGNC; HGNC:5477; IGH; Name(s)=IGH-BCL6 (DOI=10.1182/blood.V118.21.5210.5210).
CC   Sequence variation: Gene fusion; HGNC; HGNC:990; BCL2 + HGNC; HGNC:5853; IGL; Name(s)=IGL-BCL2 (DOI=10.1182/blood.V118.21.5210.5210).
CC   Sequence variation: Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (DOI=10.1182/blood.V118.21.5210.5210).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C131913; High grade B-cell lymphoma with MYC, BCL2, and BCL6 rearrangements
DI   ORDO; Orphanet_480541; High grade B-cell lymphoma with MYC and/or BCL2 and/or BCL6 rearrangement
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   60Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 14
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RX   DOI=10.1182/blood.V118.21.5210.5210;
RA   Tsunekawa N., Hanamura I., Yamamoto H., Nagoshi H., Wakabayashi M.,
RA   Sakamoto N., Horio T., Gotoh M., Mizuno S., Takahashi M., Suganuma K.,
RA   Goto M., Hiramatsu A., Watarai M., Shikami M., Imamura A., Mihara H.,
RA   Taki T., Taniwaki M., Miwa H., Nitta M.;
RT   "Establishment and characterization of a novel human cell line of
RT   triple hit lymphoma, AMU-ML1, carrying t(2;18)(p11.2;q21) and
RT   t(3;8;14)(q27;q24;q32) that involve BCL2, BCL6 and MYC.";
RL   Blood 118 Suppl. 1:5210a-5210a(2011).
//