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Cellosaurus CMA-03 (CVCL_M486)

[Text version]
Cell line name CMA-03
Synonyms CMA03
Accession CVCL_M486
Resource Identification Initiative To cite this cell line use: CMA-03 (RRID:CVCL_M486)
Comments Characteristics: Produces IgG kappa.
Characteristics: IL6 dependent.
Doubling time: 80 hours (PubMed=16266902).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Peritoneal effusion; UBERON=UBERON_0001268.
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_2G61 (CMA-03/06)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=16266902
Verdelli D., Mattioli M., Fabris S., Nobili L., Intini D., Guerneri S., Todoerti K., Zanella A., Lambertenghi-Deliliers G., Lombardi L., Neri A.
Molecular and biological characterization of three novel interleukin-6-dependent human myeloma cell lines.
Haematologica 90:1541-1548(2005)

PubMed=17171682; DOI=10.1002/gcc.20404
Lombardi L., Poretti G., Mattioli M., Fabris S., Agnelli L., Bicciato S., Kwee I., Rinaldi A., Ronchetti D., Verdelli D., Lambertenghi-Deliliers G., Bertoni F., Neri A.
Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.
Genes Chromosomes Cancer 46:226-238(2007)

PubMed=18700954; DOI=10.1186/1755-8794-1-37; PMCID=PMC2531129
Ronchetti D., Lionetti M., Mosca L., Agnelli L., Andronache A., Fabris S., Lambertenghi-Deliliers G., Neri A.
An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma.
BMC Med. Genomics 1:37.1-37.9(2008)

PubMed=19306352; DOI=10.1002/gcc.20660
Lionetti M., Agnelli L., Mosca L., Fabris S., Andronache A., Todoerti K., Ronchetti D., Lambertenghi-Deliliers G., Neri A.
Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.
Genes Chromosomes Cancer 48:521-531(2009)

PubMed=24327544; DOI=10.1002/gcc.22127
Verdelli D., Nobili L., Todoerti K., Mosca L., Fabris S., D'Anca M., Pellegrino E., Piva R., Inghirami G., Capelli C., Introna M., Baldini L., Chiaramonte R., Lombardi L., Neri A.
Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line.
Genes Chromosomes Cancer 53:154-167(2014)

Cross-references
Encyclopedic resources Wikidata; Q54813731
Experimental variables resources EFO; EFO_0006552
Gene expression databases GEO; GSM143344
GEO; GSM290288
GEO; GSM977751
GEO; GSM977752
GEO; GSM977753
GEO; GSM977754
GEO; GSM977755
GEO; GSM977756
Polymorphism and mutation databases Cosmic; 2391808
Entry history
Entry creation05-Nov-2013
Last entry update10-Sep-2024
Version number13