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Cellosaurus REN (CVCL_M202)

[Text version]
Cell line name REN
Synonyms Ren
Accession CVCL_M202
Resource Identification Initiative To cite this cell line use: REN (RRID:CVCL_M202)
Comments Characteristics: Established from a SCID nude mouse xenograft (PubMed=8010779).
Miscellaneous: STR profile from personal communication of Pentimalli, Francesca.
Miscellaneous: Sex and age of donor and site of origin from personal communication of Smythe, William Roy through Pentimalli, Francesca.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C8CW (REN/green)CVCL_C8CX (REN/luc)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
Publications

PubMed=8010779; DOI=10.1016/0003-4975(94)90090-6
Smythe W.R., Kaiser L.R., Hwang H.C., Amin K.M., Pilewski J.M., Eck S.L., Wilson J.M., Albelda S.M.
Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma.
Ann. Thorac. Surg. 57:1395-1401(1994)

PubMed=8174104
Smythe W.R., Hwang H.C., Amin K.M., Eck S.L., Davidson B.L., Wilson J.M., Kaiser L.R., Albelda S.M.
Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system.
Cancer Res. 54:2055-2059(1994)

PubMed=12063468; DOI=10.1067/mtc.2002.121684
Smythe W.R., Mohuiddin I., Ozveran M., Cao X.-B.
Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product.
J. Thorac. Cardiovasc. Surg. 123:1191-1198(2002)

PubMed=12707267; DOI=10.1074/jbc.M302161200
Vivo C., Liu W.-H., Broaddus V.C.
c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells.
J. Biol. Chem. 278:25461-25467(2003)

PubMed=18223230; DOI=10.1158/1078-0432.CCR-07-1388
Bertino P., Piccardi F., Porta C., Favoni R.E., Cilli M., Mutti L., Gaudino G.
Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts.
Clin. Cancer Res. 14:541-548(2008)

PubMed=22552293; DOI=10.1158/0008-5472.CAN-11-3481; PMCID=PMC3389268
Jube S., Rivera Z.S., Bianchi M.E., Powers A., Wang E., Pagano I., Pass H.I., Gaudino G., Carbone M., Yang H.-N.
Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma.
Cancer Res. 72:3290-3301(2012)

Cross-references
Encyclopedic resources Wikidata; Q54949728
Experimental variables resources EFO; EFO_0022351
Polymorphism and mutation databases Cosmic; 1963334
Entry history
Entry creation06-May-2013
Last entry update10-Sep-2024
Version number12