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Cellosaurus COG-LL-329h (CVCL_M162)

[Text version]
Cell line name COG-LL-329h
Accession CVCL_M162
Resource Identification Initiative To cite this cell line use: COG-LL-329h (RRID:CVCL_M162)
Comments Characteristics: Hypoxic cell line grown at 5% O2.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B3TI ! COG-LL-329
CVCL_B3TJ ! COG-LL-332
CVCL_M163 ! COG-LL-332h
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133817,19
D3S135815
D5S81810,13
D7S8208,12
D8S117910,13
D13S31712
D16S53912
D18S5117,18
D19S43313.2,15
D21S1129,31.2
FGA25,26
TH016,8
TPOX8,10
vWA15,16

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Web pages https://www.cccells.org/cellreqs-leuk.php
https://www.cccells.org/PDF_Files/LL-PDX/COG-LL-329.pdf
Publications

PubMed=22137317; DOI=10.1016/j.leukres.2011.10.022; PMCID=PMC3264762
Zhang C., Ryu Y.-K., Chen T.Z., Hall C.P., Webster D.R., Kang M.H.
Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
Leuk. Res. 36:342-349(2012)

PubMed=26080839; DOI=10.1158/1078-0432.CCR-15-0114; PMCID=PMC4681691
Hall C.P., Reynolds C.P., Kang M.H.
Modulation of glucocorticoid resistance in pediatric T-cell acute lymphoblastic leukemia by increasing BIM expression with the PI3K/mTOR inhibitor BEZ235.
Clin. Cancer Res. 22:621-632(2016)

PubMed=28119491; DOI=10.1158/1535-7163.MCT-16-0749
Makena M.R., Koneru B., Nguyen T.H., Kang M.H., Reynolds C.P.
Reactive oxygen species-mediated synergism of fenretinide and romidepsin in preclinical models of T-cell lymphoid malignancies.
Mol. Cancer Ther. 16:649-661(2017)

Cross-references
Encyclopedic resources Wikidata; Q54813972
Entry history
Entry creation06-May-2013
Last entry update02-May-2024
Version number12