Cell line name |
HT-29/B6 |
Synonyms |
HT29/B6 |
Accession |
CVCL_LJ30 |
Resource Identification Initiative |
To cite this cell line use: HT-29/B6 (RRID:CVCL_LJ30) |
Comments |
Population: Caucasian. Characteristics: Derived from a glucose-free culture of HT-29. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
|
Disease |
Colon adenocarcinoma (NCIt: C4349) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0320 (HT-29) |
Sex of cell |
Female |
Age at sampling |
44Y |
Category |
Cancer cell line |
Publications | PubMed=1656765; DOI=10.1152/ajpcell.1991.261.4.C574 Kreusel K.-M., Fromm M., Schulzke J.-D., Hegel U. Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6). Am. J. Physiol. 261:C574-C582(1991) PubMed=11533143; DOI=10.1111/j.1469-7793.2001.00541.x; PMCID=PMC2278785 Bojarski C., Gitter A.H., Bendfeldt K., Mankertz J., Schmitz H., Wagner S., Fromm M., Schulzke J.-D. Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis. J. Physiol. (Lond.) 535:541-552(2001) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_LJ30
|
Encyclopedic resources |
Wikidata; Q54896526
|
Entry history |
Entry creation | 15-Nov-2017 |
Last entry update | 19-Dec-2024 |
Version number | 16 |
---|