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Cellosaurus SC263 R10.2 (CVCL_LI56)

[Text version]
Cell line name SC263 R10.2
Accession CVCL_LI56
Resource Identification Initiative To cite this cell line use: SC263 R10.2 (RRID:CVCL_LI56)
Comments Selected for resistance to: DrugBank; DB00002; Cetuximab (Erbitux).
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.704_735del32; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified (from parent cell line).
Disease Head and neck squamous cell carcinoma (NCIt: C34447)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_LI51 (NKI-SC263)
Category Cancer cell line
Publications

PubMed=26269754; PMCID=PMC4529614
Boeckx C., Blockx L., Op de Beeck K., Limame R., Van Camp G., Peeters M., Vermorken J.B., Specenier P., Wouters A., Baay M., Lardon F.
Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.
Am. J. Cancer Res. 5:1921-1938(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LI56
Encyclopedic resources Wikidata; Q54952247
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number9