Cell line name |
CWR-R1ca |
Accession |
CVCL_LI36 |
Resource Identification Initiative |
To cite this cell line use: CWR-R1ca (RRID:CVCL_LI36) |
Comments |
Population: Caucasian. Characteristics: Fibroblast-free derivative of CWR-R1. Derived from site: In situ; Prostate; UBERON=UBERON_0002367. |
Sequence variations |
- Mutation; HGNC; 644; AR; Simple; p.His875Tyr (c.2623C>T); ClinVar=VCV000009834; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Gln331Arg (c.992A>G); ClinVar=VCV000421319; Zygosity=Unspecified (from parent cell line).
|
Disease |
Prostate carcinoma (NCIt: C4863) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_4833 (CWR-R1) |
Sex of cell |
Male |
Age at sampling |
Adult |
Category |
Cancer cell line |
STR profile |
Source(s): Millipore=SCC118; PubMed=27271795
Markers:Amelogenin | X,Y |
CSF1PO | 10,11 |
D3S1358 | 12,13,14 (Millipore=SCC118) 13,14,15 (PubMed=27271795) |
D5S818 | 11,12 |
D7S820 | 9,10,12 |
D8S1179 | 13,14 |
D13S317 | 8,12 (PubMed=27271795) 8,12,13 (Millipore=SCC118) |
D16S539 | 12 |
D18S51 | 13,14,15 (Millipore=SCC118) 14,15 (PubMed=27271795) |
D21S11 | 29,30 (Millipore=SCC118) 30 (PubMed=27271795) |
FGA | 20,21,23 (Millipore=SCC118) 20,23 (PubMed=27271795) |
Penta D | 8,9,12 (Millipore=SCC118) 9,12 (PubMed=27271795) |
Penta E | 5,13 |
TH01 | 6,9.3 |
TPOX | 8 |
vWA | 15,16,18,19 (Millipore=SCC118) 15,19 (PubMed=27271795) |
Run an STR similarity search on this cell line |
Publications | PubMed=27271795; DOI=10.1002/pros.23190 Shourideh M., DePriest A., Mohler J.L., Wilson E.M., Koochekpour S. Characterization of fibroblast-free CWR-R1ca castration-recurrent prostate cancer cell line. Prostate 76:1067-1077(2016) |
Cross-references |
Cell line collections (Providers) |
Millipore; SCC118
|
Cell line databases/resources |
cancercelllines; CVCL_LI36
|
Encyclopedic resources |
Wikidata; Q54817051
|
Entry history |
Entry creation | 15-Nov-2017 |
Last entry update | 02-May-2024 |
Version number | 12 |
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