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Cellosaurus GHOST(3)-CXCR4 DRiP78 and NHERF1 knockdown (CVCL_LI04)

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Cell line name GHOST(3)-CXCR4 DRiP78 and NHERF1 knockdown
Accession CVCL_LI04
Resource Identification Initiative To cite this cell line use: GHOST(3)-CXCR4 DRiP78 and NHERF1 knockdown (RRID:CVCL_LI04)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:24581; DNAJC14.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11075; NHERF1.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2561; CXCR4.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_S492 (GHOST(3).CXCR4)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=26018859; PMCID=PMC4790691
Zhang L., Huang X.-H., Zhou P.-P., Yu G.-L., Yan J., Qin B., Yan X.-G., Diao L.-M., Lin P., Kuang Y.-Q.
Establishment of HIV-1 model cell line GHOST(3) with stable DRiP78 and NHERF1 knockdown.
Dong Wu Xue Yan Jiu 36:161-166(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LI04
Encyclopedic resources Wikidata; Q54835799
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number15