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Cellosaurus AG04059 (CVCL_L623)

[Text version]
Cell line name AG04059
Synonyms AG-4059; AG 4059; AG04059B; GRC#0179
Accession CVCL_L623
Resource Identification Initiative To cite this cell line use: AG04059 (RRID:CVCL_L623)
Comments Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
Population: Caucasian.
Doubling time: Slow growth (Coriell=AG04059).
Karyotypic information: 46,XY [94%]; 45,X [6%] (Coriell=AG04059).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 96Y
Category Finite cell line
Publications

PubMed=7307581; DOI=10.1159/000131624
Schneider E.L., Monticone R., Smith J.R., Braunschweiger K.I., Roberts T.W.
Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging.
Cytogenet. Cell Genet. 31:40-46(1981)

PubMed=7176709; DOI=10.1016/0047-6374(82)90061-6
Tollefsbol T.O., Zaun M.R., Gracy R.W.
Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts.
Mech. Ageing Dev. 20:93-101(1982)

PubMed=6223188; DOI=10.1016/0047-6374(83)90071-4
Chapman M.L., Zaun M.R., Gracy R.W.
Changes in NAD levels in human lymphocytes and fibroblasts during aging and in premature aging syndromes.
Mech. Ageing Dev. 21:157-167(1983)

PubMed=6538202; DOI=10.1083/jcb.98.3.1133; PMCID=PMC2113122
Azzarone B., Suarez H.G., Mingari M.C., Moretta L., Fauci A.S.
4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin.
J. Cell Biol. 98:1133-1137(1984)

PubMed=3374507; DOI=10.1016/0027-5107(88)90211-4
Azzarone B., Chaponnier C., Krief P., Mareel M.M., Suarez H.G., Macieira-Coelho A.
Human fibroblasts from cancer patients: lifespan and transformed phenotype in vitro and role of mesenchyme in vivo.
Mutat. Res. 199:313-325(1988)

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=10741968; DOI=10.1126/science.287.5462.2486
Ly D.H., Lockhart D.J., Lerner R.A., Schultz P.G.
Mitotic misregulation and human aging.
Science 287:2486-2492(2000)

PubMed=30567591; DOI=10.1186/s13059-018-1599-6; PMCID=PMC6300908
Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A., Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.
Predicting age from the transcriptome of human dermal fibroblasts.
Genome Biol. 19:221.1-221.8(2018)

Cross-references
Cell line collections (Providers) Coriell; AG04059
Cell line databases/resources CLO; CLO_0034766
Encyclopedic resources Wikidata; Q54609911
Gene expression databases GEO; GSM3124624
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number15