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Cellosaurus AG05247 (CVCL_L605)

[Text version]
Cell line name AG05247
Synonyms AG05247D; AG05247E; GRC#0445
Accession CVCL_L605
Resource Identification Initiative To cite this cell line use: AG05247 (RRID:CVCL_L605)
Comments Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
Population: Caucasian.
Senescence: Senesces at 45 PDL (PubMed=9724752).
Karyotypic information: 46,XX [45]; 46,XX,t(2;6)(2pter->2q23::6q21->6qter;6pter->6q21::2q23->2qter) [3]; 46,XX,t(7;18)(7qter->7p22::18q21->18qter;18pter->18q21::7p22->7pter) [2] (Coriell=AG05247).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L607 ! AG09602
Sex of cell Female
Age at sampling 87Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=9724752; DOI=10.1073/pnas.95.18.10614; PMCID=PMC27943
Cristofalo V.J., Allen R.G., Pignolo R.J., Martin B.G., Beck J.C.
Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation.
Proc. Natl. Acad. Sci. U.S.A. 95:10614-10619(1998)

PubMed=16081512; DOI=10.1093/carcin/bgi204
Khan S.G., Oh K.-S., Shahlavi T., Ueda T., Busch D.B., Inui H., Emmert S., Imoto K., Muniz-Medina V., Baker C.C., DiGiovanna J.J., Schmidt D., Khadavi A., Metin A., Gozukara E.M., Slor H., Sarasin A., Kraemer K.H.
Reduced XPC DNA repair gene mRNA levels in clinically normal parents of xeroderma pigmentosum patients.
Carcinogenesis 27:84-94(2006)

PubMed=28855503; DOI=10.1038/s41467-017-00322-z; PMCID=PMC5577202
Buchwalter A., Hetzer M.W.
Nucleolar expansion and elevated protein translation in premature aging.
Nat. Commun. 8:328.1-328.13(2017)

PubMed=30567591; DOI=10.1186/s13059-018-1599-6; PMCID=PMC6300908
Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A., Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.
Predicting age from the transcriptome of human dermal fibroblasts.
Genome Biol. 19:221.1-221.8(2018)

Cross-references
Cell line collections (Providers) Coriell; AG05247
Cell line databases/resources CLO; CLO_0035154
Encyclopedic resources Wikidata; Q54739823
Gene expression databases GEO; GSM3124615
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number15