ID   AG05247
AC   CVCL_L605
SY   AG05247D; AG05247E; GRC#0445
DR   CLO; CLO_0035154
DR   Coriell; AG05247
DR   GEO; GSM3124615
DR   Wikidata; Q54739823
RX   CelloPub=CLPUB00597;
RX   PubMed=9724752;
RX   PubMed=16081512;
RX   PubMed=28855503;
RX   PubMed=30567591;
CC   Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
CC   Population: Caucasian.
CC   Senescence: Senesces at 45 PDL (PubMed=9724752).
CC   Karyotypic information: 46,XX [45]; 46,XX,t(2;6)(2pter->2q23::6q21->6qter;6pter->6q21::2q23->2qter) [3]; 46,XX,t(7;18)(7qter->7p22::18q21->18qter;18pter->18q21::7p22->7pter) [2] (Coriell=AG05247).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_L607 ! AG09602
SX   Female
AG   87Y
CA   Finite cell line
DT   Created: 06-05-13; Last updated: 29-06-23; Version: 15
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RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994).
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RX   PubMed=9724752; DOI=10.1073/pnas.95.18.10614;
RA   Cristofalo V.J., Allen R.G., Pignolo R.J., Martin B.G., Beck J.C.;
RT   "Relationship between donor age and the replicative lifespan of human
RT   cells in culture: a reevaluation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:10614-10619(1998).
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RX   PubMed=16081512; DOI=10.1093/carcin/bgi204;
RA   Khan S.G., Oh K.-S., Shahlavi T., Ueda T., Busch D.B., Inui H.,
RA   Emmert S., Imoto K., Muniz-Medina V., Baker C.C., DiGiovanna J.J.,
RA   Schmidt D., Khadavi A., Metin A., Gozukara E.M., Slor H., Sarasin A.,
RA   Kraemer K.H.;
RT   "Reduced XPC DNA repair gene mRNA levels in clinically normal parents
RT   of xeroderma pigmentosum patients.";
RL   Carcinogenesis 27:84-94(2006).
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RX   PubMed=28855503; DOI=10.1038/s41467-017-00322-z;
RA   Buchwalter A., Hetzer M.W.;
RT   "Nucleolar expansion and elevated protein translation in premature
RT   aging.";
RL   Nat. Commun. 8:328.1-328.13(2017).
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RX   PubMed=30567591; DOI=10.1186/s13059-018-1599-6;
RA   Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A.,
RA   Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.;
RT   "Predicting age from the transcriptome of human dermal fibroblasts.";
RL   Genome Biol. 19:221.1-221.8(2018).
//