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Cellosaurus G401.6 (CVCL_L269)

[Text version]
Cell line name G401.6
Accession CVCL_L269
Resource Identification Initiative To cite this cell line use: G401.6 (RRID:CVCL_L269)
Comments Problematic cell line: Misclassified. Parent cell line (G-401) was originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line.
Part of: ENCODE project common cell types; tier 3.
Population: Caucasian.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Homozygous (from parent cell line).
Disease Rhabdoid tumor of the kidney (NCIt: C8715)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0270 (G-401)
Sex of cell Male
Age at sampling 3M
Category Cancer cell line
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/MRTG401.6_Crawford_protocol.pdf

PubMed=3031816; DOI=10.1126/science.3031816
Weissman B.E., Saxon P.J., Pasquale S.R., Jones G.R., Geiser A.G., Stanbridge E.J.
Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression.
Science 236:175-180(1987)

Biological sample resources ENCODE; ENCBS257AAA
Encyclopedic resources Wikidata; Q54835399
Experimental variables resources EFO; EFO_0005703
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number15