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Cellosaurus WM165-1 (CVCL_L033)

[Text version]
Cell line name WM165-1
Synonyms WM-165-1; WM 165-1
Accession CVCL_L033
Resource Identification Initiative To cite this cell line use: WM165-1 (RRID:CVCL_L033)
Comments Part of: Wistar Institute melanoma cell line collection.
Population: Caucasian.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Hemizygous (Wistar).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Asp (c.1799_1800delTGinsAT); ClinVar=VCV000375939; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0040 ! WM115
CVCL_RN55 ! WM165-2
CVCL_6795 ! WM239A
CVCL_RN56 ! WM239B
CVCL_RN57 ! WM266-1
CVCL_RN58 ! WM266-2
CVCL_RN59 ! WM266-3
CVCL_2765 ! WM266-4
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO12
D2S133819
D3S135815,18
D5S81813
D7S8208
D8S117913,15
D13S31712
D16S53911,12
D18S5115,17
D19S43313
D21S1129
FGA21,23
TH017,9
TPOX8,11
vWA15,17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Herlyn M., Balaban G.B., Bennicelli J.L., Guerry D. IV, Halaban R., Herlyn D., Elder D.E., Maul G.G., Steplewski Z., Nowell P.C., Clark W.H. Jr., Koprowski H.
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Herlyn M., Thurin J., Balaban G.B., Bennicelli J.L., Herlyn D., Elder D.E., Bondi E., Guerry D. IV, Nowell P.C., Clark W.H. Jr., Koprowski H.
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM165-1-01-0001
Cell line databases/resources cancercelllines; CVCL_L033
Cell_Model_Passport; SIDM00977
Encyclopedic resources Wikidata; Q54994189
Entry history
Entry creation06-May-2013
Last entry update05-Oct-2023
Version number19