Cellosaurus WM115 (CVCL_0040)
Cell line name | WM115 | ||||||||||||||||||||||||||||||||
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Synonyms | WM-115; WM 115; WM115F; WM115-mel; WM115mel; WC00079 | ||||||||||||||||||||||||||||||||
Accession | CVCL_0040 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: WM115 (RRID:CVCL_0040) | ||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: MD Anderson Cell Lines Project. Part of: Wistar Institute melanoma cell line collection. Population: Caucasian. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep antibody staining analysis. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: CSF1PO: 11,12->12, D18S51: 17->17,21 and D8S1179: 8,13->13,15. Misspelling: WH115mel; CGH-DB=9323-4. Derived from site: Metastatic; Right anterior leg, skin; UBERON=UBERON_0001511. | ||||||||||||||||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=15592718
Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Melanoma (NCIt: C3224) | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Originate from same individual | CVCL_L033 ! WM165-1 CVCL_RN55 ! WM165-2 CVCL_6795 ! WM239A CVCL_RN56 ! WM239B CVCL_RN57 ! WM266-1 CVCL_RN58 ! WM266-2 CVCL_RN59 ! WM266-3 CVCL_2765 ! WM266-4 | ||||||||||||||||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||||||||||||||||
Age at sampling | 55Y | ||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=CRL-1675; Cosmic-CLP=909784; ESTDAB=ESTDAB-066; Wistar Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | https://www.proteinatlas.org/learn/cellines https://www.wistar.org/our-scientists/meenhard-herlyn https://tcpaportal.org/mclp/ | ||||||||||||||||||||||||||||||||
Publications | PubMed=3856042; DOI=10.1093/jnci/74.2.283 PubMed=4053039 PubMed=3020539; DOI=10.1073/pnas.83.19.7197; PMCID=PMC386682 PubMed=2253310; DOI=10.1007/BF00046337 PubMed=11121133; DOI=10.1046/j.1523-1747.2000.00199.x PubMed=15009714; DOI=10.1046/j.0022-202X.2004.22243.x; PMCID=PMC2586668 PubMed=15467732; DOI=10.1038/sj.onc.1208152 PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966 PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=21424129; DOI=10.3892/or.2011.1220 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-1675 - Discontinued
Coriell; WC00079 - Discontinued ECACC; 91061232 - Discontinued IZSLER; BS TCL 74 Rockland; WM115-01-0001 | ||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0009613
CLDB; cl4727 CLDB; cl4728 cancercelllines; CVCL_0040 Cell_Model_Passport; SIDM01000 CGH-DB; 9323-4 Cosmic-CLP; 909784 DepMap; ACH-000304 ESTDAB; ESTDAB-066 IGRhCellID; WM115 LINCS_HMS; 50567 LINCS_LDP; LCL-1260 Lonza; 584 | ||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0003075 | ||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN10987773 | ||||||||||||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 345 | ||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308813
ChEMBL-Targets; CHEMBL1075611 GDSC; 909784 PharmacoDB; WM115_1662_2019 PubChem_Cell_line; CVCL_0040 | ||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54994157 | ||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002390 | ||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM109022 GEO; GSM827472 GEO; GSM887735 GEO; GSM888830 GEO; GSM1670576 | ||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 886835
Cosmic; 888868 Cosmic; 897480 Cosmic; 905236 Cosmic; 909784 Cosmic; 932717 Cosmic; 972277 Cosmic; 1155268 Cosmic; 1155547 Cosmic; 1238102 Cosmic; 1238104 IARC_TP53; 21271 IARC_TP53; 24992 LiGeA; CCLE_370 Progenetix; CVCL_0040 | ||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000610
EGA; EGAS00001000978 EGA; EGAS00001002554 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||
Version number | 46 |