Cellosaurus InCELL Hunter U2OS MCL1-BIM Protein Binding (CVCL_KW15)
| Cell line name | InCELL Hunter U2OS MCL1-BIM Protein Binding |
|---|---|
| Accession | CVCL_KW15 |
| Resource Identification Initiative | To cite this cell line use: InCELL Hunter U2OS MCL1-BIM Protein Binding (RRID:CVCL_KW15) |
| Comments | Population: Caucasian. Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6943; MCL1. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:994; BCL2L11 (Note=With p.Met1_Asp141del and p.Tyr162_His198del). Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979. |
| Sequence variations |
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| Disease | Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0042 (U2OS) |
| Sex of cell | Female |
| Age at sampling | 15Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | DiscoverX; 96-0075C3 |
| Encyclopedic resources | Wikidata; Q54897730 |
| Entry history | |
| Entry creation | 22-Aug-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 10 |