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Cellosaurus CellSensor NFAT-bla RA-1 (CVCL_KS46)

[Text version]
Cell line name CellSensor NFAT-bla RA-1
Synonyms NFAT-bla RA-1
Accession CVCL_KS46
Resource Identification Initiative To cite this cell line use: CellSensor NFAT-bla RA-1 (RRID:CVCL_KS46)
Comments Population: Caucasian.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of the NFAT response element.
Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Web pages https://www.thermofisher.com/order/catalog/product/K1490
Cross-references
Encyclopedic resources Wikidata; Q54809206
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number14