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Cellosaurus 184 (CVCL_K049)

[Text version]
Cell line name 184
Synonyms HMEC-184; HMEC 184; HMEC184
Accession CVCL_K049
Resource Identification Initiative To cite this cell line use: 184 (RRID:CVCL_K049)
Comments Senescence: Senesces at ~80 PDL (PubMed=9398663).
Doubling time: 2.5 days (PubMed=9671407).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_K053 (184-hTERT)CVCL_3040 (184A1)CVCL_4688 (184B5)
CVCL_B0AX (184E6E7)
Sex of cell Female
Age at sampling 21Y
Category Finite cell line
Web pages https://hmec.lbl.gov/mreview.htm

PubMed=8504475; DOI=10.1093/carcin/14.5.833
Lehman T.A., Modali R., Boukamp P., Stanek J., Bennett W.P., Welsh J.A., Metcalf R.A., Stampfer M.R., Fusenig N.E., Rogan E.M., Harris C.C.
p53 mutations in human immortalized epithelial cell lines.
Carcinogenesis 14:833-839(1993)

PubMed=9398663; DOI=10.1091/mbc.8.12.2391
Stampfer M.R., Bodnar A.G., Garbe J.C., Wong M., Pan A., Villeponteau B., Yaswen P.
Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells.
Mol. Biol. Cell 8:2391-2405(1997)

PubMed=9671407; DOI=10.1038/sj.onc.1201814
Sweeney K.J., Swarbrick A., Sutherland R.L., Musgrove E.A.
Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells.
Oncogene 16:2865-2878(1998)

PubMed=10739701; DOI=10.1006/gyno.2000.5734
Annab L.A., Terry L., Cable P.L., Brady J., Stampfer M.R., Barrett J.C., Afshari C.A.
Establishment and characterization of a breast cell strain containing a BRCA1 185delAG mutation.
Gynecol. Oncol. 77:121-128(2000)

Encyclopedic resources Wikidata; Q54582473
Experimental variables resources EFO; EFO_0001190
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number12