Cellosaurus cell line C5.2 (CVCL

Cellosaurus C5.2 (CVCL_J984)

Cross-references
Cell line name	C5.2
Synonyms	HB4a-C5.2
Accession	CVCL_J984
Resource Identification Initiative	To cite this cell line use: C5.2 (RRID:CVCL_J984)
Comments	Characteristics: High expression of ERBB2 (PubMed=9935193). Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3430; ERBB2. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58+U19). Omics: Transcriptome analysis by massively parallel signature sequencing (MPSS). Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367. Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_J982 (HB4a)
Sex of cell	Female
Age at sampling	18Y
Category	Conditionally immortalized cell line
Publications	PubMed=9935193; DOI=10.1002/(SICI)1097-0215(19990129)80:3<477::AID-IJC23>3.0.CO;2-W Harris R.A., Eichholtz T.J., Hiles I.D., Page M.J., O'Hare M.J. New model of ErbB-2 over-expression in human mammary luminal epithelial cells. Int. J. Cancer 80:477-484(1999) CLPUB00734 Silva A.P.M., Carraro D.M., Pires L.C., Jongeneel C.V., De Souza S.J., Camargo A.A. Characterization of novel c-erbB2 regulated genes using massively parallel signature sequencing (MPSS). Cancer Res. 66 Suppl. 8:19-20(2006) PubMed=16685446; DOI=10.3892/ijo.28.6.1441 dos Santos M.L., Palanch C.G., Salaorni S., da Silva W.A. Jr., Nagai M.A. Transcriptome characterization of human mammary cell lines expressing different levels of ERBB2 by serial analysis of gene expression. Int. J. Oncol. 28:1441-1461(2006)
Encyclopedic resources	Wikidata; Q54808190
Entry history
Entry creation	11-Feb-2013
Last entry update	19-Dec-2024
Version number	14