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Cellosaurus HBT-39b (CVCL_J652)

[Text version]
Cell line name HBT-39b
Synonyms HBT-39B; HBT39B; HBT39b; HBT-39; HT-39
Accession CVCL_J652
Resource Identification Initiative To cite this cell line use: HBT-39b (RRID:CVCL_J652)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=884688; PubMed=1246601; PubMed=4469665; PubMed=6451928; PubMed=20143388). Originally thought to originate from a breast carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00053.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=4122211; DOI=10.1093/jnci/50.4.849
Plata E.J., Aoki T., Robertson D.D., Chu E.W., Gerwin B.I.
An established cultured cell line (HBT-39) from human breast carcinoma.
J. Natl. Cancer Inst. 50:849-862(1973)

PubMed=4469665; DOI=10.1126/science.184.4141.1093
Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.
Banded marker chromosomes as indicators of intraspecies cellular contamination.
Science 184:1093-1096(1974)

Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

Lippman M.E., Bolan G., Huff K.
The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture.
Cancer Res. 36:4595-4601(1976)

Lippman M.E., Bolan G., Huff K.
The effects of androgens and antiandrogens on hormone-responsive human breast cancer in long-term tissue culture.
Cancer Res. 36:4610-4618(1976)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

Nelson-Rees W.A.
Three papers on hormones and breast cancer in vitro.
Cancer Res. 37:3464-3465(1977)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151700
Encyclopedic resources Wikidata; Q54881459
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number20