ID   HBT-39b
AC   CVCL_J652
SY   HBT-39B; HBT39B; HBT39b; HBT-39; HT-39
DR   BioSample; SAMN03151700
DR   Wikidata; Q54881459
RX   CelloPub=CLPUB00262;
RX   DOI=10.1007/978-1-4757-1647-4_13;
RX   PubMed=884688;
RX   PubMed=1000504;
RX   PubMed=1000506;
RX   PubMed=1246601;
RX   PubMed=4122211;
RX   PubMed=4469665;
RX   PubMed=6451928;
RX   PubMed=20143388;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=884688; PubMed=1246601; PubMed=4469665; PubMed=6451928; PubMed=20143388). Originally thought to originate from a breast carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00053.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 05-10-23; Version: 20
RX   CelloPub=CLPUB00262;
RA   Gold M.;
RT   "A conspiracy of cells. One woman's immortal legacy and the medical
RT   scandal it caused.";
RL   (In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986).
RX   DOI=10.1007/978-1-4757-1647-4_13;
RA   Biedler J.L.;
RT   "Chromosome abnormalities in human tumor cells in culture.";
RL   (In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975).
RX   PubMed=884688;
RA   Nelson-Rees W.A.;
RT   "Three papers on hormones and breast cancer in vitro.";
RL   Cancer Res. 37:3464-3465(1977).
RX   PubMed=1000504;
RA   Lippman M.E., Bolan G., Huff K.;
RT   "The effects of estrogens and antiestrogens on hormone-responsive
RT   human breast cancer in long-term tissue culture.";
RL   Cancer Res. 36:4595-4601(1976).
RX   PubMed=1000506;
RA   Lippman M.E., Bolan G., Huff K.;
RT   "The effects of androgens and antiandrogens on hormone-responsive
RT   human breast cancer in long-term tissue culture.";
RL   Cancer Res. 36:4610-4618(1976).
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
RX   PubMed=4122211; DOI=10.1093/jnci/50.4.849;
RA   Plata E.J., Aoki T., Robertson D.D., Chu E.W., Gerwin B.I.;
RT   "An established cultured cell line (HBT-39) from human breast
RT   carcinoma.";
RL   J. Natl. Cancer Inst. 50:849-862(1973).
RX   PubMed=4469665; DOI=10.1126/science.184.4141.1093;
RA   Nelson-Rees W.A., Flandermeyer R.R., Hawthorne P.K.;
RT   "Banded marker chromosomes as indicators of intraspecies cellular
RT   contamination.";
RL   Science 184:1093-1096(1974).
RX   PubMed=6451928; DOI=10.1126/science.6451928;
RA   Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.;
RT   "Cross-contamination of cells in culture.";
RL   Science 212:446-452(1981).
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).