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Cellosaurus A549/8 (CVCL_IY87)

[Text version]
Cell line name A549/8
Accession CVCL_IY87
Resource Identification Initiative To cite this cell line use: A549/8 (RRID:CVCL_IY87)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_3901 (EA.hy 926)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=94594; DOI=10.1002/ijc.2910240622
Edgell C.-J.S., Gazdar A.F., Minna J.D.
Expression of feline xenotropic RNA tumor virus in hybrids between permissive human and non-permissive mouse cells.
Int. J. Cancer 24:826-834(1979)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IY87
Encyclopedic resources Wikidata; Q54607043
Entry history
Entry creation15-May-2017
Last entry update19-Dec-2024
Version number11