• Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
  

PubMed=6407019; DOI=10.1073/pnas.80.12.3734; PMCID=PMC394125
Edgell C.-J.S., McDonald C.C., Graham J.B.
Permanent cell line expressing human factor VIII-related antigen established by hybridization.
Proc. Natl. Acad. Sci. U.S.A. 80:3734-3737(1983)

PubMed=3130908; DOI=10.1182/blood.V71.6.1669.1669
Emeis J.J., Edgell C.-J.S.
Fibrinolytic properties of a human endothelial hybrid cell line (Ea.hy 926).
Blood 71:1669-1675(1988)

PubMed=7791520; DOI=10.1016/0024-3205(95)00227-W
Ahn K., Pan S., Beningo K., Hupe D.
A permanent human cell line (EA.hy926) preserves the characteristics of endothelin converting enzyme from primary human umbilical vein endothelial cells.
Life Sci. 56:2331-2341(1995)

PubMed=12453433; DOI=10.1006/mvre.2002.2434
Unger R.E., Krump-Konvalinkova V., Peters K., Kirkpatrick C.J.
In vitro expression of the endothelial phenotype: comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1.6R.
Microvasc. Res. 64:384-397(2002)

PubMed=16575254; DOI=10.1097/01.mbc.0000220237.99843.a1
Boerma M., Burton G.R., Wang J.-R., Fink L.M., McGehee R.E. Jr., Hauer-Jensen M.
Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition.
Blood Coagul. Fibrinolysis 17:173-180(2006)

PubMed=26345505; DOI=10.2144/000114326
Lieber D., Hochdorfer D., Stoehr D., Schubert A., Lotfi R., May T., Wirth D., Sinzger C.
A permanently growing human endothelial cell line supports productive infection with human cytomegalovirus under conditional cell growth arrest.
BioTechniques 59:127-136(2015)

PubMed=28199884; DOI=10.1016/j.biomaterials.2017.02.005
Pietsch J., Gass S., Nebuloni S., Echegoyen D., Riwaldt S., Baake C., Bauer J., Corydon T.J., Egli M., Infanger M., Grimm D.
Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission -- the SPHEROIDS project.
Biomaterials 124:126-156(2017)

PubMed=30108515; DOI=10.3389/fphys.2018.01025; PMCID=PMC6079262
Li N., Wang C.-Z., Sun S.-J., Zhang C., Lu D.-Y., Chen Q., Long M.
Microgravity-induced alterations of inflammation-related mechanotransduction in endothelial cells on board SJ-10 satellite.
Front. Physiol. 9:1025.1-1025.15(2018)

PubMed=30977987; DOI=10.33594/000000071
Kruger M., Pietsch J., Bauer J., Kopp S., Carvalho D.T.O., Baatout S., Moreels M., Melnik D., Wehland M., Egli M., Sahana J., Kobbero S.D., Corydon T.J., Nebuloni S., Gass S., Evert M., Infanger M., Grimm D.
Growth of endothelial cells in space and in simulated microgravity -- a comparison on the secretory level.
Cell. Physiol. Biochem. 52:1039-1060(2019)